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1

Antitumor Activity and Biomarker Analysis of Sunitinib in Patients With Bevacizumab-Refractory Metastatic Renal Cell Carcinoma

Rini, B. I., Michaelson, M. D., Rosenberg, J. E., Bukowski, R. M., Sosman, J. A., Stadler, W. M., Hutson, T. E., Margolin, K., Harmon, C. S., DePrimo, S. E., Kim, S. T., Chen, I., George, D. J.

Journal:

Journal of Clinical Oncology

Year:

2008

Language:

english

File:

PDF, 211 KB

english, 2008

2

Toreforant, an orally active histamine H4-receptor antagonist, in patients with active rheumatoid arthritis despite methotrexate: mechanism of action results from a phase 2, multicenter, randomized, double-blind, placebo-controlled synovial biopsy study

Boyle, David L., DePrimo, Samuel E., Calderon, Cesar, Chen, Dion, Dunford, Paul J., Barchuk, William, Firestein, Gary S., Thurmond, Robin L.

Journal:

Inflammation Research

Year:

2019

File:

PDF, 1.07 MB

2019

3

Ustekinumab for the treatment of moderateâtoâsevere plaque psoriasis in pediatric patients (â¥6 to

Philipp, S., Menter, A., Nikkels, A.F., Barber, K., Landells, I., Eichenfield, L.F., Song, M., Randazzo, B., Li, S., Hsu, M.âC., Zhu, Y., DePrimo, S., Paller, A.S.

Journal:

British Journal of Dermatology

Year:

2020

Language:

english

File:

PDF, 857 KB

english, 2020

4

Mechanism-related circulating proteins as biomarkers for clinical outcome in patients with unresectable hepatocellular carcinoma receiving sunitinib

Charles S Harmon, Samuel E DePrimo, Eric Raymond, Ann-Lii Cheng, Eveline Boucher, Jean-Yves Douillard, Ho Y Lim, Jun S Kim, Maria José Lechuga, Silvana Lanzalone, Xun Lin, Sandrine Faivre

Journal:

Journal of Translational Medicine

Year:

2011

Language:

english

File:

PDF, 722 KB

english, 2011

5

Human placental alkaline phosphatase as a histochemical marker of gene expression in transgenic mice

Samuel E. Deprimo, Peter J. Stambrook, James R. Stringer

Journal:

Transgenic Research

Year:

1996

Language:

english

File:

PDF, 1.63 MB

english, 1996

6

Cell-line and tissue-specific signatures of androgen receptor-coregulator transcription

Jan-Hendrik Bebermeier, James D. Brooks, Samuel E. DePrimo, Ralf Werner, Uta Deppe, Janos Demeter, Olaf Hiort, Paul-Martin Holterhus

Journal:

Journal of Molecular Medicine

Year:

2006

Language:

english

File:

PDF, 669 KB

english, 2006

7

Regulation of p53 expression by the RAS-MAP kinase pathway

Agarwal, Munna L, Ramana, Chilakamarti V, Hamilton, Mark, Taylor, William R, DePrimo, Samuel E, Bean, Lora JH, Agarwal, Archana, Agarwal, Mukesh K, Wolfman, Alan, Stark, George R

Journal:

Year:

2001

Language:

english

File:

PDF, 245 KB

english, 2001

8

Cell cycle dependence of radiation-induced homologous recombination in cultured monkey cells

J Cao, S.E DePrimo, J.R Stringer

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

1997

Language:

english

File:

PDF, 255 KB

english, 1997

9

In situ detection of frameshift mutation in mouse cells

Jianmin Cao, Samuel E DePrimo, Megan N Hersh, James R Stringer

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

1998

Language:

english

File:

PDF, 381 KB

english, 1998

10

CO.47 Les biomarqueurs plasmatiques peuvent prédire la réponse et la survie des patients atteints de carcinomes hépatocellulaires (CHC) avancés traités par sunitinib

S. Faivre, C. Dreyer, S. Dokmak, M. Zappa, S. Deprimo, F. Degos, A. Chengx, V. Vilgrain, J. Belghiti, E. Raymond

Journal:

Gastroentérologie Clinique et Biologique

Year:

2009

Language:

french

File:

PDF, 96 KB

french, 2009

11

Expression profiling of blood samples from an SU5416 Phase III metastatic colorectal cancer clinical trial: a novel strategy for biomarker identification

Samuel E DePrimo, Lily M Wong, Deepak B Khatry, Susan L Nicholas, William C Manning, Beverly D Smolich, Anne-Marie O'Farrell, Julie M Cherrington

Journal:

Year:

2003

Language:

english

File:

PDF, 415 KB

english, 2003

12

Use of Human Placental Alkaline Phosphatase Transgenes to Detect Somatic Mutation in Micein Situ

Samuel E. DePrimo, Jianmin Cao, Megan N. Hersh, James R. Stringer

Journal:

Year:

1998

Language:

english

File:

PDF, 1.38 MB

english, 1998

13

Clinical evaluation of continuous daily dosing of sunitinib malate in patients with advanced gastrointestinal stromal tumour after imatinib failure

S. George, J.Y. Blay, P.G. Casali, A. Le Cesne, P. Stephenson, S.E. DePrimo, C.S. Harmon, C.N.J. Law, J.A. Morgan, I. Ray-Coquard, V. Tassell, D.P. Cohen, G.D. Demetri

Journal:

European Journal of Cancer

Year:

2009

Language:

english

File:

PDF, 523 KB

english, 2009

14

Safety and efficacy of sunitinib in patients with advanced hepatocellular carcinoma: an open-label, multicentre, phase II study

Sandrine Faivre, Eric Raymond, Eveline Boucher, Jean Douillard, Ho Y Lim, Jun S Kim, Magaly Zappa, Silvana Lanzalone, Xun Lin, Samuel DePrimo, Charles Harmon, Ana Ruiz-Garcia, Maria J Lechuga, Ann Lii

Journal:

The Lancet Oncology

Year:

2009

Language:

english

File:

PDF, 178 KB

english, 2009

15

57 POSTER Correlation of receptor tyrosine kinase (RTK) activity and paoptosis with response to sunitinib treatment in patients with gastrointestinal stromal tumor (GIST)

D.W. Davis, D.J. McConkey, J.V. Heymach, J. Desai, S. George, S.E. DePrimo, C.L. Bello, C.M. Baum, G.D. Demetri

Journal:

European Journal of Cancer Supplements

Year:

2006

Language:

english

File:

PDF, 73 KB

english, 2006

16

Soluble KIT correlates with clinical outcome in patients with metastatic breast cancer treated with sunitinib

Kiana Keyvanjah, Samuel E DePrimo, Charles S Harmon, Xin Huang, Kenneth A Kern, William Carley

Journal:

Journal of Translational Medicine

Year:

2012

Language:

english

File:

PDF, 439 KB

english, 2012

17

Circulating protein biomarkers of pharmacodynamic activity of sunitinib in patients with metastatic renal cell carcinoma: modulation of VEGF and VEGF-related proteins

Samuel E DePrimo, Carlo L Bello, John Smeraglia, Charles M Baum, Dominic Spinella, Brian I Rini, Dror M Michaelson, Robert J Motzer

Journal:

Journal of Translational Medicine

Year:

2007

Language:

english

File:

PDF, 442 KB

english, 2007

18

Transcriptional programs activated by exposure of human prostate cancer cells to androgen

Samuel E DePrimo, Maximilian Diehn, Joel B Nelson, Robert E Reiter…

Journal:

Year:

2002

Language:

english

File:

PDF, 330 KB

english, 2002

19

Circulating proteins as potential biomarkers of sunitinib and interferon-α efficacy in treatment-naïve patients with metastatic renal cell carcinoma

Harmon, Charles S., DePrimo, Samuel E., Figlin, Robert A., Hudes, Gary R., Hutson, Thomas E., Michaelson, M. Dror, Négrier, Sylvie, Kim, Sindy T., Huang, Xin, Williams, J. Andrew, Eisen, Tim, Motzer,

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2014

Language:

english

File:

PDF, 294 KB

english, 2014

20

PREVENTION OF PROSTATE CANCER

DePrimo, Samuel E., Shinghal, Rajesh, Vidanes, Genevieve, Brooks, James D.

Journal:

Hematology/Oncology Clinics of North America

Year:

2001

Language:

english

File:

PDF, 843 KB

english, 2001

21

7502 ORAL Assessment of plasma levels of soluble KIT (sKIT) as a potential surrogate marker for TTP in patients (pts) with advanced gastrointestinal stromal tumor (GIST) treated with sunitinib

Schoffski, P., Huang, X., Demetri, G.D., Casali, P.G., Garrett, C.R., Blackstein, M., Shah, M.H., Verweij, J., Baum, C.M., DePrimo, S.E.

Journal:

European Journal of Cancer Supplements

Year:

2007

Language:

english

File:

PDF, 77 KB

english, 2007

22

Phase I Pharmacokinetic and Pharmacodynamic Study of the Oral MAPK/ERK Kinase Inhibitor PD-0325901 in Patients with Advanced Cancers

LoRusso, P. M., Krishnamurthi, S. S., Rinehart, J. J., Nabell, L. M., Malburg, L., Chapman, P. B., DePrimo, S. E., Bentivegna, S., Wilner, K. D., Tan, W., Ricart, A. D.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 684 KB

english, 2010

23

Phase II Study of Sunitinib Malate, an Oral Multitargeted Tyrosine Kinase Inhibitor, in Patients With Metastatic Breast Cancer Previously Treated With an Anthracycline and a Taxane

Burstein, H. J., Elias, A. D., Rugo, H. S., Cobleigh, M. A., Wolff, A. C., Eisenberg, P. D., Lehman, M., Adams, B. J., Bello, C. L., DePrimo, S. E., Baum, C. M., Miller, K. D.

Journal:

Journal of Clinical Oncology

Year:

2008

Language:

english

File:

PDF, 183 KB

english, 2008

24

Circulating Levels of Soluble KIT Serve as a Biomarker for Clinical Outcome in Gastrointestinal Stromal Tumor Patients Receiving Sunitinib following Imatinib Failure

DePrimo, S. E., Huang, X., Blackstein, M. E., Garrett, C. R., Harmon, C. S., Schoffski, P., Shah, M. H., Verweij, J., Baum, C. M., Demetri, G. D.

Journal:

Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 331 KB

english, 2009

25

Surrogate biomarkers in evaluating response to anti-angiogenic agents: focus on sunitinib

DePrimo, S., Bello, C

Journal:

Annals of Oncology

Year:

2007

Language:

english

File:

PDF, 227 KB

english, 2007

26

Blood-Based Biomarkers of SU11248 Activity and Clinical Outcome in Patients with Metastatic Imatinib-Resistant Gastrointestinal Stromal Tumor

Norden-Zfoni, A., Desai, J., Manola, J., Beaudry, P., Force, J., Maki, R., Folkman, J., Bello, C., Baum, C., DePrimo, S. E., Shalinsky, D. R., Demetri, G. D., Heymach, J. V.

Journal:

Clinical Cancer Research

Year:

2007

Language:

english

File:

PDF, 543 KB

english, 2007

27

Mechanisms of G2 Arrest in Response to Overexpression of p53

Taylor, W. R., DePrimo, S. E., Agarwal, A., Agarwal, M. L., Schonthal, A. H., Katula, K. S., Stark, G. R.

Journal:

Molecular Biology of the Cell

Year:

1999

Language:

english

File:

PDF, 556 KB

english, 1999

28

Circulating cytokines and monocyte subpopulations as biomarkers of outcome and biological activity in sunitinib-treated patients with advanced neuroendocrine tumours

Zurita, A J, Khajavi, M, Wu, H-K, Tye, L, Huang, X, Kulke, M H, Lenz, H-J, Meropol, N J, Carley, W, DePrimo, S E, Lin, E, Wang, X, Harmon, C S, Heymach, J V

Journal:

British Journal of Cancer

Year:

2015

Language:

english

File:

PDF, 415 KB

english, 2015

29

Phase II Trial of Sunitinib in Patients With Metastatic Colorectal Cancer After Failure of Standard Therapy

Saltz, L. B., Rosen, L. S., Marshall, J. L., Belt, R. J., Hurwitz, H. I., Eckhardt, S. G., Bergsland, E. K., Haller, D. G., Lockhart, A. C., Rocha Lima, C. M., Huang, X., DePrimo, S. E., Chow-Maneval,

Journal:

Journal of Clinical Oncology

Year:

2007

Language:

english

File:

PDF, 159 KB

english, 2007

30

Longitudinal study of the psoriasis-associated skin microbiome during therapy with ustekinumab in a randomized Phase 3b clinical trial

Loesche, Michael, Farahi, Kamyar, Capone, Kimberly, Fakharzadeh, Steven, Blauvelt, Andrew, Duffin, Kristina Callis, DePrimo, Samuel E., Muñoz-Elías, Ernesto J., Brodmerkel, Carrie, Dasgupta, Bidisha,

Journal:

The Journal of Investigative Dermatology

Year:

2018

Language:

english

File:

PDF, 1.00 MB

english, 2018

31

451 Association between HLA-Cw6 status and response to guselkumab in patients with moderate to severe plaque psoriasis

Liu, X., DePrimo, S., Chen, Y., Li, S., Munoz-Elias, E.

Journal:

The Journal of Investigative Dermatology

Year:

2018

Language:

english

File:

PDF, 238 KB

english, 2018

32

Comprehensive Medicinal Chemistry II || Biomarkers

Year:

2007

Language:

english

File:

PDF, 196 KB

english, 2007

33

Toreforant, an orally active histamine H4-receptor antagonist, in patients with active rheumatoid arthritis despite methotrexate: mechanism of action results from a phase 2, multicenter, randomized, double-blind, placebo-controlled synovial biopsy study

Boyle, David L., DePrimo, Samuel E., Calderon, Cesar, Chen, Dion, Dunford, Paul J., Barchuk, William, Firestein, Gary S., Thurmond, Robin L.

Journal:

Inflammation Research

Year:

2019

Language:

english

File:

PDF, 1.07 MB

english, 2019

34

The Case Files

DePrimo, Kathryn M., Malik, Khalid

Journal:

Emergency Medicine News

Year:

2019

File:

PDF, 280 KB

2019

35

Broad proteomic screen reveals shared serum proteomic signature in patients with psoriatic arthritis and psoriasis without arthritis

Leijten, Emmerik, Tao, Weiyang, Pouw, Juliette, van Kempen, Tessa, Olde Nordkamp, Michel, Balak, Deepak, Tekstra, J, MuÃ±oz-ElÃas, Ernesto, DePrimo, Samuel, Drylewicz, Julia, Pandit, Aridaman, Boes,

Journal:

Year:

2020

File:

PDF, 716 KB

2020